The Whitehouse Rescue Squad responded with local police to the crash off Higginsville Road in Readington and found the trapped victims around 7:30 a.m., the squad said.
The crash occurred near the intersection with Niki's Way, initial reports said.
WRS used water rescue techniques to safely extricate the pair before transporting them to a local trauma center for treatment of serious injuries.
The Three Bridges Volunteer Fire Company also responded to assist with traffic control, WRS said.
Scroll down to view additional photos from the crash scene.
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